Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload

Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload

  • Author: Marcel A. Vieira-Lara , Marleen B
  • Yili: 2021
  • Bo‘lim: JURNALLAR
  • Ko‘rishlar: 3
  • Fayl: Mavjud
Kirish Ro‘yxatdan o‘tish

Summary: The skeletal muscle plays a central role in glucose homeostasis through the uptake of glucose from the extracellular medium in response to insulin. A number of factors are known to disrupt the normal response to insulin leading to the emergence of insulin resistance (IR). Advanced age and a high-fat diet are factors that increase the susceptibility to IR, with lipid accumulation in the skeletal muscle being a key driver of this phenomenon. It is debated, however, whether lipid accumulation arises due to dietary lipid overload or from a decline of mitochondrial function. CPT1B pasayishi va lipidlarning haddan tashqari ko'payishi

  • Kitob ID: 5104
  • Format: PDF / Elektron kitob
  • Yaratilgan sana: 2026-07-22 15:11:36
  • Ko‘rishlar soni: 3
Kitobni o‘qish va yuklab olish uchun avval tizimga kiring.

Kirish Ro‘yxatdan o‘tish
Kitob tavsifi

The skeletal muscle plays a central role in glucose homeostasis through the uptake of glucose from
the extracellular medium in response to insulin. A number of factors are known to disrupt the normal response to insulin leading to the emergence of insulin resistance (IR). Advanced age and a high-fat diet are factors that increase the susceptibility to IR, with lipid accumulation in the skeletal muscle being a key driver of this phenomenon. It is debated, however, whether lipid accumulation arises due to dietary lipid overload or from a decline of mitochondrial function.

CPT1B pasayishi va lipidlarning haddan tashqari ko'payishi

Maydon Qiymat
ID5104
NomiAge-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload
MuallifMarcel A. Vieira-Lara , Marleen B
Bo‘limJURNALLAR
Nashr yili2021
Ko‘rishlar3
Fayl hajmi 2.8 MB
Yaratilgan sana2026-07-22 15:11:36
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